Interplay between oxidative stress, SIRT1, reproductive and metabolic functions
نویسندگان
چکیده
منابع مشابه
Interplay between Oxidative Stress and Metabolism in Signalling and Disease
It is well recognized that energy metabolism is linked to the production of reactive species and critical enzymatic processes allied to metabolic pathways can be affected by redox reactions. Both protein and lipid oxidation are involved in the aging process as well as the onset and progression of many age-related diseases. As such, the capacity to identify specific targets and detect subsequent...
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Vitiligo is a multifactorial polygenic disorder with a complex pathogenesis, linked with both genetic and non-genetic factors. The precise modus operandi for vitiligo pathogenesis has remained elusive. Theories regarding loss of melanocytes are based on autoimmune, cytotoxic, oxidant-antioxidant and neural mechanisms. Reactive oxygen species (ROS) in excess have been documented in active vitili...
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Neurodegenerative processes may be involved in the pathogenesis of schizophrenia. Brain-derived neurotrophic factor (BDNF), the most widely distributed neurotrophin and oxidative stress (OS) may be critical for several pathological manifestations of neurodegenerative disorders. Accumulating evidence suggests that both BDNF and OS may be involved in the pathophysiology of schizophrenia. However,...
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Around 50–60% of adults in western countries are either overweight or obese with more than 25% falling into the obese category [1]. The metabolic imbalance underlying obesity has fueled the prevalence of cardiometabolic syndrome— a constellation of interrelated risk factors of metabolic origins that together promote the increased risk of cardiovascular disease (CVD) and type II diabetes [2]. Th...
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Abstract Objective: Globally, 3-5.2 percent of people suffer from diabetes which is one of the most serious metabolic disorders resulting in an increase in inflammatory biomarkers e.g. interleukin-6, tumor necrosis factor-alpha, and C-reactive protein. The aim of this study was to investigate the relationship between inflammation, oxidative stress and fasting blood glucose, lipid profile and a...
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ژورنال
عنوان ژورنال: Current Research in Physiology
سال: 2021
ISSN: 2665-9441
DOI: 10.1016/j.crphys.2021.03.002